Safety Data Sheet according to Regulation (EC) No 1907/2006
Page 1 of 11
SDS No. : 153496
V006.1
LOCTITE 573 Revision: 16.03.2018
printing date: 20.12.2019
Replaces version from: 20.12.2016
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1. Product identifier
LOCTITE 573
1.2. Relevant identified uses of the substance or mixture and uses advised against
Intended use:
Anaerobic Adhesive
1.3. Details of the supplier of the safety data sheet
Henkel Ltd
Wood Lane End
HP2 4RQ Hemel Hempstead
Great Britain
Phone: +44 1442 278000
Fax-no.: +44 1442 278071
[Link]@[Link]
1.4. Emergency telephone number
24 Hours Emergency Tel: +44 (0)1442 278497
SECTION 2: Hazards identification
2.1. Classification of the substance or mixture
Classification (CLP):
The substance or mixture is not hazardous according to Regulation (EC) No 1272/2008 (CLP).
2.2. Label elements
Label elements (CLP):
The substance or mixture is not hazardous according to Regulation (EC) No 1272/2008 (CLP).
Supplemental information EUH210 Safety data sheet available on request.
2.3. Other hazards
None if used properly.
Not fulfilling Persistent, Bioaccumulative and Toxic (PBT), very Persistent and very Bioaccumulative (vPvB) criteria.
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SECTION 3: Composition/information on ingredients
3.2. Mixtures
General chemical description:
Anaerobic adhesive
Declaration of the ingredients according to CLP (EC) No 1272/2008:
Hazardous components EC Number content Classification
CAS-No. REACH-Reg No.
Cumene hydroperoxide 201-254-7 0,1- < 1 % Acute Tox. 4; Dermal
80-15-9 H312
STOT RE 2
H373
Acute Tox. 4; Oral
H302
Org. Perox. E
H242
Acute Tox. 3; Inhalation
H331
Aquatic Chronic 2
H411
Skin Corr. 1B
H314
For full text of the H - statements and other abbreviations see section 16 "Other information".
Substances without classification may have community workplace exposure limits available.
SECTION 4: First aid measures
4.1. Description of first aid measures
Inhalation:
Move to fresh air. If symptoms persist, seek medical advice.
Skin contact:
Rinse with running water and soap.
Seek medical advice.
Eye contact:
Rinse immediately with plenty of running water (for 10 minutes). Seek medical attention if necessary.
Ingestion:
Rinse out mouth, drink 1-2 glasses of water, do not induce vomiting.
Seek medical advice.
4.2. Most important symptoms and effects, both acute and delayed
Prolonged or repeated contact may cause skin irritation.
Prolonged or repeated contact may cause eye irritation.
4.3. Indication of any immediate medical attention and special treatment needed
See section: Description of first aid measures
SECTION 5: Firefighting measures
5.1. Extinguishing media
Suitable extinguishing media:
Carbon dioxide, foam, powder
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Extinguishing media which must not be used for safety reasons:
None known
5.2. Special hazards arising from the substance or mixture
In the event of a fire, carbon monoxide (CO), carbon dioxide (CO2) and nitrogen oxides (NOx) can be released.
Sulphur oxides
Irritating vapours.
5.3. Advice for firefighters
Wear self-contained breathing apparatus and full protective clothing, such as turn-out gear.
Additional information:
In case of fire, keep containers cool with water spray.
SECTION 6: Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures
Avoid contact with skin and eyes.
Ensure adequate ventilation.
Wear protective equipment.
6.2. Environmental precautions
Do not empty into drains / surface water / ground water.
6.3. Methods and material for containment and cleaning up
For small spills wipe up with paper towel and place in container for disposal.
For large spills absorb onto inert absorbent material and place in sealed container for disposal.
Dispose of contaminated material as waste according to Section 13.
SECTION 7: Handling and storage
7.1. Precautions for safe handling
Use only in well-ventilated areas.
Prolonged or repeated skin contact should be avoided to minimise any risk of sensitisation.
Avoid skin and eye contact.
See advice in section 8
Hygiene measures:
Good industrial hygiene practices should be observed.
Wash hands before work breaks and after finishing work.
Do not eat, drink or smoke while working.
7.2. Conditions for safe storage, including any incompatibilities
Refer to Technical Data Sheet
7.3. Specific end use(s)
Anaerobic Adhesive
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SECTION 8: Exposure controls/personal protection
8.1. Control parameters
Occupational Exposure Limits
Valid for
Great Britain
Ingredient [Regulated substance] ppm mg/m3 Value type Short term exposure limit Regulatory list
category / Remarks
Silicon dioxide 6 Time Weighted Average EH40 WEL
112945-52-5 (TWA):
[SILICA, AMORPHOUS, INHALABLE
DUST]
Silicon dioxide 2,4 Time Weighted Average EH40 WEL
112945-52-5 (TWA):
[SILICA, AMORPHOUS, RESPIRABLE
DUST]
Occupational Exposure Limits
Valid for
Ireland
Ingredient [Regulated substance] ppm mg/m3 Value type Short term exposure limit Regulatory list
category / Remarks
Silicon dioxide 6 Time Weighted Average IR_OEL
112945-52-5 (TWA):
[SILICA, AMORPHOUS, TOTAL
INHALABLE DUST]
Silicon dioxide 2,4 Time Weighted Average IR_OEL
112945-52-5 (TWA):
[SILICA, AMORPHOUS, RESPIRABLE
DUST]
Predicted No-Effect Concentration (PNEC):
Name on list Environmental Exposure Value Remarks
Compartment period
mg/l ppm mg/kg others
.alpha.,.alpha.-Dimethylbenzyl aqua 0,0031
hydroperoxide (freshwater) mg/l
80-15-9
.alpha.,.alpha.-Dimethylbenzyl aqua (marine 0,00031
hydroperoxide water) mg/l
80-15-9
.alpha.,.alpha.-Dimethylbenzyl aqua 0,031 mg/l
hydroperoxide (intermittent
80-15-9 releases)
.alpha.,.alpha.-Dimethylbenzyl Sewage 0,35 mg/l
hydroperoxide treatment plant
80-15-9
.alpha.,.alpha.-Dimethylbenzyl sediment 0,023
hydroperoxide (freshwater) mg/kg
80-15-9
.alpha.,.alpha.-Dimethylbenzyl sediment 0,0023
hydroperoxide (marine water) mg/kg
80-15-9
.alpha.,.alpha.-Dimethylbenzyl soil 0,0029
hydroperoxide mg/kg
80-15-9
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Derived No-Effect Level (DNEL):
Name on list Application Route of Health Effect Exposure Value Remarks
Area Exposure Time
.alpha.,.alpha.-Dimethylbenzyl Workers inhalation Long term 6 mg/m3
hydroperoxide exposure -
80-15-9 systemic effects
Biological Exposure Indices:
None
8.2. Exposure controls:
Engineering controls:
Ensure good ventilation/extraction.
Respiratory protection:
Use only in well-ventilated areas.
An approved mask or respirator fitted with an organic vapour cartridge should be worn if the product is used in a poorly
ventilated area
Filter type: A (EN 14387)
Hand protection:
Chemical-resistant protective gloves (EN 374).
Suitable materials for short-term contact or splashes (recommended: at least protection index 2, corresponding to > 30 minutes
permeation time as per EN 374):
nitrile rubber (NBR; >= 0.4 mm thickness)
Suitable materials for longer, direct contact (recommended: protection index 6, corresponding to > 480 minutes permeation time
as per EN 374):
nitrile rubber (NBR; >= 0.4 mm thickness)
This information is based on literature references and on information provided by glove manufacturers, or is derived by analogy
with similar substances. Please note that in practice the working life of chemical-resistant protective gloves may be considerably
shorter than the permeation time determined in accordance with EN 374 as a result of the many influencing factors (e.g.
temperature). If signs of wear and tear are noticed then the gloves should be replaced.
Eye protection:
Safety glasses with sideshields or chemical safety goggles should be worn if there is a risk of splashing.
Protective eye equipment should conform to EN166.
Skin protection:
Wear suitable protective clothing.
Protective clothing should conform to EN 14605 for liquid splashes or to EN 13982 for dusts.
Advices to personal protection equipment:
The information provided on personal protective equipment is for guidance purposes only. A full risk assessment should be
conducted prior to using this product to determine the appropriate personal protective equipment to suit local conditions.
Personal protective equipment should conform to the relevant EN standard.
SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties
Appearance paste
paste
green
Odor characteristic
Odour threshold No data available / Not applicable
pH 3,00 - 6,00
()
Melting point No data available / Not applicable
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Solidification temperature No data available / Not applicable
Initial boiling point > 150,0 °C (> 302 °F)
Flash point > 93,3 °C (> 199.94 °F); Tagliabue closed cup
Evaporation rate No data available / Not applicable
Flammability No data available / Not applicable
Explosive limits No data available / Not applicable
Vapour pressure < 0,27 mbar
Vapour pressure < 300 mbar
(50 °C (122 °F))
Relative vapour density: No data available / Not applicable
Density 1,0800 g/cm3
()
Bulk density No data available / Not applicable
Solubility No data available / Not applicable
Solubility (qualitative) Not miscible
(Solvent: Water)
Partition coefficient: n-octanol/water No data available / Not applicable
Auto-ignition temperature No data available / Not applicable
Decomposition temperature No data available / Not applicable
Viscosity No data available / Not applicable
Viscosity (kinematic) No data available / Not applicable
Explosive properties No data available / Not applicable
Oxidising properties No data available / Not applicable
9.2. Other information
No data available / Not applicable
SECTION 10: Stability and reactivity
10.1. Reactivity
Reaction with strong acids.
Reacts with strong oxidants.
10.2. Chemical stability
Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
See section reactivity
10.4. Conditions to avoid
Stable
10.5. Incompatible materials
See section reactivity.
10.6. Hazardous decomposition products
carbon oxides.
Sulphur oxides
nitrogen oxides
Irritating organic vapours.
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SECTION 11: Toxicological information
General toxicological information:
Prolonged or repeated contact may cause skin irritation.
Prolonged or repeated contact may cause eye irritation.
11.1. Information on toxicological effects
Acute oral toxicity:
This material is considered to have low toxicity if swallowed.
Hazardous substances Value Value Species Method
CAS-No. type
Cumene hydroperoxide LD50 550 mg/kg rat not specified
80-15-9
Acute dermal toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Value Value Species Method
CAS-No. type
Cumene hydroperoxide LD50 1.200 - 1.520 not specified
80-15-9 mg/kg
Acute inhalative toxicity:
No substance data available.
No data available.
Skin corrosion/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Result Exposure Species Method
CAS-No. time
Cumene hydroperoxide corrosive rabbit Draize Test
80-15-9
Serious eye damage/irritation:
No data available.
Respiratory or skin sensitization:
No substance data available.
No data available.
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances Result Type of study / Metabolic Species Method
CAS-No. Route of activation /
administration Exposure time
Cumene hydroperoxide positive bacterial reverse without OECD Guideline 471
80-15-9 mutation assay (e.g (Bacterial Reverse Mutation
Ames test) Assay)
Cumene hydroperoxide negative dermal mouse not specified
80-15-9
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Carcinogenicity
No data available.
Reproductive toxicity:
No data available.
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances Result / Value Route of Exposure time / Species Method
CAS-No. application Frequency of
treatment
Cumene hydroperoxide inhalation: 6 h/d rat not specified
80-15-9 aerosol 5 d/w
Aspiration hazard:
No data available.
SECTION 12: Ecological information
General ecological information:
Cured Loctite products are typical polymers and do not pose any immediate environmental hazards.
Do not empty into drains / surface water / ground water.
12.1. Toxicity
Toxicity (Fish):
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Value Value Exposure time Species Method
CAS-No. type
Cumene hydroperoxide LC50 3,9 mg/l 96 h Oncorhynchus mykiss OECD Guideline 203 (Fish,
80-15-9 Acute Toxicity Test)
Toxicity (Daphnia):
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Value Value Exposure time Species Method
CAS-No. type
Cumene hydroperoxide EC 50 7 mg/l 24 h Water flea (Daphnia magna)
80-15-9
Cumene hydroperoxide EC50 18 mg/l 48 h Daphnia magna OECD Guideline 202
80-15-9 (Daphnia sp. Acute
Immobilisation Test)
Chronic toxicity to aquatic invertebrates
No data available.
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Toxicity (Algae):
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Value Value Exposure time Species Method
CAS-No. type
Cumene hydroperoxide ErC50 3,1 mg/l 72 h Pseudokirchneriella subcapitata OECD Guideline 201 (Alga,
80-15-9 Growth Inhibition Test)
Toxicity to microorganisms
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances Value Value Exposure time Species Method
CAS-No. type
Cumene hydroperoxide EC10 70 mg/l 30 min not specified
80-15-9
12.2. Persistence and degradability
The product is not biodegradable.
Hazardous substances Result Test type Degradability Exposure Method
CAS-No. time
Cumene hydroperoxide no data 0% 28 d OECD Guideline 301 B (Ready
80-15-9 Biodegradability: CO2 Evolution
Test)
12.3. Bioaccumulative potential
Does not bioaccumulate.
Hazardous substances Bioconcentratio Exposure time Temperature Species Method
CAS-No. n factor (BCF)
Cumene hydroperoxide 9,1 calculation OECD Guideline 305
80-15-9 (Bioconcentration: Flow-through
Fish Test)
12.4. Mobility in soil
Cured adhesives are immobile.
Hazardous substances LogPow Temperature Method
CAS-No.
Cumene hydroperoxide 2,16 not specified
80-15-9
12.5. Results of PBT and vPvB assessment
Hazardous substances PBT / vPvB
CAS-No.
Cumene hydroperoxide Not fulfilling Persistent, Bioaccumulative and Toxic (PBT), very Persistent and very
80-15-9 Bioaccumulative (vPvB) criteria.
12.6. Other adverse effects
No data available.
SECTION 13: Disposal considerations
13.1. Waste treatment methods
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Product disposal:
Dispose of in accordance with local and national regulations.
Contribution of this product to waste is very insignificant in comparison to article in which it is used
Disposal of uncleaned packages:
After use, tubes, cartons and bottles containing residual product should be disposed of as chemically contaminated waste in an
authorised legal land fill site or incinerated.
Waste code
08 04 09 waste adhesives and sealants containing organic solvents and other dangerous substances
The valid EWC waste code numbers are source-related. The manufacturer is therefore unable to specify EWC waste codes
for the articles or products used in the various sectors. The EWC codes listed are intended as a recommendation for users. We
will be happy to advise you.
SECTION 14: Transport information
14.1. UN number
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.2. UN proper shipping name
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.3. Transport hazard class(es)
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.4. Packing group
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.5. Environmental hazards
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.6. Special precautions for user
Not hazardous according to RID, ADR, ADN, IMDG, IATA-DGR.
14.7. Transport in bulk according to Annex II of Marpol and the IBC Code
not applicable
SECTION 15: Regulatory information
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
VOC content < 3,00 %
(2010/75/EC)
15.2. Chemical safety assessment
A chemical safety assessment has not been carried out.
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SECTION 16: Other information
The labelling of the product is indicated in Section 2. The full text
of all abbreviations indicated by codes in this safety data sheet are as follows:
H242 Heating may cause a fire.
H302 Harmful if swallowed.
H312 Harmful in contact with skin.
H314 Causes severe skin burns and eye damage.
H331 Toxic if inhaled.
H373 May cause damage to organs through prolonged or repeated exposure.
H411 Toxic to aquatic life with long lasting effects.
Further information:
This information is based on our current level of knowledge and relates to the product in the state in which it is delivered. It is
intended to describe our products from the point of view of safety requirements and is not intended to guarantee any particular
properties.
Relevant changes in this safety data sheet are indicated by vertical lines at the left margin in the body of this document.
Corresponding text is displayed in a different color on shadowed fields.
