Safety Data Sheet according to GB/T 16483 and GB/T 17519
Page 1 of 10 .
LOCTITE 401 BO20KG Material No.: 282144
V001.9
Revision: 20.02.2025
printing date: 14.07.2025
1. Identification of the substance/preparation and of the company/undertaking
Product name: LOCTITE 401 BO20G
Intended use: Adhesive
Manufacturer/Importer/Distributor Representative Company
Henkel Adhesive Technology (Shanghai) Co., Ltd.
Room 105, 2B (Building 1), No. 928, Zhangheng Road,China (Shanghai) Pilot Free Trade Zone
201204 Pudong New Area, Shanghai, [Link]
China
Phone: +86 (21) 2891 8000
Fax-no.: +86 (21) 2891 5137
E-mail: [Link]@[Link]
Revision date: 20.02.2025
Emergency Telephone for +86 21 2891 8311 (24h).
Chemical Accidents:
2. Hazards identification
EMERGENCY OVERVIEW:
Colorless / Colourless to light yellow, Sharp, liquid, Combustible [Link] skin [Link] serious eye
[Link] cause respiratory irritation.
Classification of the substance or mixture according to GB 30000.1 (Specification for classification and labelling of chemicals
—Part 1：General rules):
Hazard Class Hazard Category Target organ
Flammable liquids Category 4
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2A
Specific target organ toxicity - Category 3 respiratory tract irritation
single exposure
Label elements according to GB 15258 (General rules for preparation of precautionary label for chemicals):
Hazard pictogram:
Signal word: Warning
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LOCTITE 401 BO20G
Hazard statement: H227 Combustible liquid.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Prevention: P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources.
No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves, eye protection, and face protection.
Response: P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340+P312 IF INHALED: Remove victim to fresh air and keep at rest in a position
comfortable for breathing. Call a POISON CENTER or physician if you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P332+P313 If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/attention.
P362+P364 Take off contaminated clothing and wash it before
reuse.
P370+P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for
extinction.
Storage: P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
Disposal: P501 Dispose of contents/container to an appropriate treatment and disposal facility in
accordance with applicable laws and regulations, and product characteristics at time
of disposal.
Physical and chemical hazards:
Combustible liquid.
Health hazards:
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Environmental hazards:
Based on current information, there are no environmental hazards.
3. Composition / information on ingredients
Substance or Mixture:
Mixture
Declaration of the ingredients according to GB 30000.1:
Hazard component CAS-No. Content GHS Classification
Ethyl 2-cyanoacrylate 90- <= 100 % Flammable liquids 4
7085-85-0 H227
Skin corrosion/irritation 2
H315
Serious eye damage/eye irritation 2A
H319
Specific target organ toxicity - single exposure 3
H335
Only hazardous ingredients for which a classification according to GB 30000.1 is already available are displayed in this table. For full
text of the Hazard statements see section 16 “Other information”.
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LOCTITE 401 BO20G
4. First aid measures
Description of necessary first-aid measures:
Skin contact: Do not pull bonded skin apart. It may be gently peeled apart using a blunt object such as a
spoon, preferably after soaking in warm soapy water.
Cyanoacrylates give off heat on solidification. In rare cases a large drop will generate
enough heat to cause a burn.
Burns should be treated normally after the adhesive has been removed from the skin.
If lips are accidentally stuck together apply warm water to the lips and encourage
maximum wetting and pressure from saliva inside the mouth.
Peel or roll lips apart. Do not try to pull the lips apart with direct opposing action.
Eye contact: If the eye is bonded closed, release eyelashes with warm water by covering with wet pad.
Cyanoacrylate will bond to eye protein and will cause periods of weeping which will help
to debond the adhesive.
Keep eye covered until debonding is complete, usually within 1-3 days.
Do not force eye open. Medical advice should be sought in case solid particles of
cyanoacrylate trapped behind the eyelid cause any abrasive damage.
Inhalation: Move to fresh air, consult doctor if complaint persists.
Ingestion: Ensure that breathing passages are not obstructed. The product will polymerise
immediately in the mouth making it almost impossible to swallow. Saliva will slowly
separate the solidified product from the mouth (several hours).
Most important symptoms/effects, The most important known symptoms and effects are described in chapters 2 and/or 11.
acute and delayed:
Indication of any immediate Post-exposure treatment should focus on controlling the patient's clinical symptoms
medical attention and special and signs.
treatment needed, if necessary:
5. Fire fighting measures
Suitable extinguishing media: Foam, extinguishing powder, carbon dioxide.
Fine water spray
Fire-fighting method: In case of fire, keep containers cool with water spray.
Special protective actions for In the event of a fire, carbon monoxide (CO) and carbon dioxide (CO2) can be released.
fire- fighters: In case of fire, keep containers cool with water spray.
Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA).
6. Accidental release measures
Personal precautions, Ensure adequate ventilation.
protective equipment and
emergency
procedures:
Environmental precautions: Do not let product enter drains.
Methods and materials for Do not use cloths for mopping up. Flood with water to complete polymerization and
containment and cleaning up: scrape off the floor. Cured material can be disposed of as non-hazardous waste.
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LOCTITE 401 BO20G
7. Handling and storage
Precautions for safe handling: Ventilation (low level) is recommended when using large volumes
Use of dispensing equipment is recommended to minimise the risk of skin or eye contact
Hygiene measures: Do not eat, drink, smoke or take snuff while working.
Wash thoroughly after handling.
Keep absolute tidiness at the working [Link] contact with skin and eyes. Remove
soiled or soaked clothing immediately. Wash off any contamination that gets onto the skin
with plenty of water and soap, skin care.
Conditions for safe storage, Storage at 2 to 8°C is recommended.
including any incompatibilities:
8. Exposure controls / personal protection
Controls parameters:
Occupational Exposure Limits: no data available
Biological Exposure Indices: no data available
Engineering controls: Use positive down-draft exhaust ventilation if general ventilation is insufficient to
maintain vapor concentration below established exposure limits.
Respiratory protection: Ensure adequate ventilation.
An approved mask or respirator fitted with an organic vapour cartridge should be worn if
the product is used in a poorly ventilated area
Filter type: A (EN 14387)
Eye protection: Wear protective glasses.
Body protection: Wear suitable protective clothing.
Hand protection: The use of chemical resistant gloves such as Nitrile is recommended.
Polyethylene or polypropylene gloves are recommended when using large volumes.
9. Physical and chemical properties
Physical state: liquid Appearance: Colorless / Colourless to light
yellow
Evaporation rate: Not available. Odor: Sharp
pH: Not applicable, Product reacts Melting point: Not applicable, Product is a liquid
with water.
Boiling point: > 149 °C (> 300.2 °F) Density: 1.1 g/cm3
Vapor density: >1 Vapor pressure: Not available.
Flash point: 80 - 93 °C (176 - 199.4 °F) Ignition temperature: Not available.
Lower explosive limit: Not available. Upper explosive limit: Not available.
Solubility in water Polymerises in presence of Viscosity: 100.0 - 120.0 mPa.s70.0 - 110.0
water. mPa.s
> 20.5 mm2/s
Auto-ignition temperature: Not available. Flammability: Not available.
Octanol / water distribution Not applicable, Mixture Decomposition temperature: Not applicable, Substance/mixture
coefficient: is not self-reactive, no organic
peroxide and does not decompose
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LOCTITE 401 BO20G
under foreseen conditions of use
VOC: Bulk adhesive
α-Cyanoacrylic Acids
Assembly Industry
< 20 g/kg, GB 33372-2020 Limit of volatile organic compounds content in adhesive
10. Stability and reactivity
Reactivity: Rapid exothermic polymerization will occur in the presence of water, amines, alkalis and
alcohols.
Chemical stability: Stable under recommended storage conditions.
Possibility of hazardous reactions: None if used properly.
Conditions to avoid: Stable under normal conditions of storage and use.
Incompatible materials: None if used properly.
Hazardous decomposition carbon oxides.
products:
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LOCTITE 401 BO20G
11. Toxicological information
General toxicological information:
No laboratory animal data available.
Acute oral toxicity:
Ethyl 2-cyanoacrylate Value type LD50
7085-85-0 Value > 5,000 mg/kg
Species rat
Method equivalent or similar to OECD Guideline 423 (Acute Oral toxicity)
Acute dermal toxicity:
Ethyl 2-cyanoacrylate Value type LD50
7085-85-0 Value > 2,000 mg/kg
Species rabbit
Method equivalent or similar to OECD Guideline 402 (Acute Dermal
Toxicity)
Acute inhalative toxicity:
No data available.
Skin corrosion/irritation:
Ethyl 2-cyanoacrylate Result slightly irritating
7085-85-0 Exposure time 24 h
Species rabbit
Method equivalent or similar to OECD Guideline 404 (Acute Dermal
Irritation / Corrosion)
Serious eye damage/irritation:
Ethyl 2-cyanoacrylate Result irritating
7085-85-0 Exposure time
Species rabbit
Method equivalent or similar to OECD Guideline 405 (Acute Eye Irritation
/ Corrosion)
Respiratory or skin sensitization:
Ethyl 2-cyanoacrylate Result not sensitising
7085-85-0 Test type Guinea pig maximisation test
Species guinea pig
Method equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Germ cell mutagenicity:
Ethyl 2-cyanoacrylate Result negative
7085-85-0 Type of study / Route of administration bacterial reverse mutation assay (e.g Ames test)
Metabolic activation / Exposure time with and without
Method equivalent or similar to OECD Guideline 471 (Bacterial
Reverse Mutation Assay)
Ethyl 2-cyanoacrylate Result negative
7085-85-0 Type of study / Route of administration in vitro mammalian chromosome aberration test
Metabolic activation / Exposure time with and without
Method OECD Guideline 473 (In vitro Mammalian Chromosome
Aberration Test)
Ethyl 2-cyanoacrylate Result negative
7085-85-0 Type of study / Route of administration mammalian cell gene mutation assay
Metabolic activation / Exposure time with and without
Method OECD Guideline 476 (In vitro Mammalian Cell Gene
Mutation Test)
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LOCTITE 401 BO20G
Carcinogenicity
No data available.
Reproductive toxicity:
No data available.
STOT-single exposure:
No data available.
STOT-repeated exposure:
No data available.
Aspiration hazard:
No data available.
12. Ecological information
General ecological information:
Do not empty into drains / surface water / ground water.
Toxicity:
Toxicity (Fish):
No data available.
Toxicity (aquatic invertebrates):
No data available.
Chronic toxicity (aquatic invertebrates):
No data available.
Toxicity (Algae):
No data available.
Toxicity (microorganisms):
No data available.
Persistence and degradability
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LOCTITE 401 BO20G
Hazardous components Result Test type Degradability Exposure Method
CAS-No. time
Ethyl 2-cyanoacrylate not readily biodegradable. aerobic 57 % 28 d OECD Guideline 301 D (Ready
7085-85-0 Biodegradability: Closed Bottle
Test)
Bioaccumulative potential
Mobility in soil:
Hazardous components LogPow Temperature Method
CAS-No.
Ethyl 2-cyanoacrylate 0.776 22 °C EU Method A.8 (Partition Coefficient)
7085-85-0
Endocrine disrupting properties
No data available.
Other adverse
effects No data
available.
13. Disposal considerations
Product disposal: Dispose of in accordance with local and national regulations.
Disposal of uncleaned packages: After use, tubes, cartons and bottles containing residual product should be disposed of as
chemically contaminated waste in an authorised legal land fill site or incinerated.
14. Transport information
Road transport CN_DG:
Not dangerous goods
Marine transport IMDG:
Not dangerous goods
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LOCTITE 401 BO20G
Air transport IATA:
Class: 9
Packing group: III
Packaging instructions (passenger): 964
Packaging instructions (cargo): 964
UN no.: 3334
Label: 9
Proper shipping name: Aviation regulated liquid, n.o.s. (Cyanoacrylate ester)
Additional Information IATA: Primary packs containing less than 500ml are unregulated by this
mode of transport and may be shipped unrestricted.
Notice For Transportation: Transport according to local and national regulations. Ensure
containers will not leak, collapse, or being damaged when transported.
DO NOT transport with incompatible materials. Transportation
vehicle should be equipped with right fire-fighting equipment in case
of
emergency. Avoid solarization, drenched and high temperature when
transported.
15. Regulatory information
The following laws and regulations lay down provisions in terms of chemicals safety use, storage, transportation, loading/
unloading, classification as well as symbol.
“Law of the People's Republic of China on Work Safety”.
Law of the People's Republic of China on the Prevention and Treatment of Occupational Diseases”.
“Law of the People's Republic of China on environmental protection”.
“Regulation on the Safety Management of Hazardous Chemicals”.
“Regulations on License to Work Safety”.
China Inventory of Existing All components are listed or are exempt from Inventory of Existing Chemical
Chemicals: Substances in China.
16. Other information
Issue date: 14.07.2025
Issue department: Product Safety & Regulatory Affairs for China
RSN No.: 000000624092
Material No.: 282144
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LOCTITE 401 BO20G
Disclaimer: This Safety Data Sheet has been generated in accordance with Chinese law only. It
provides information on the chemical product in the aspects of safety, health,
environment, etc, recommending preventive and protective measures and countermeasures
in case of emergency. The information contained herein does not constitute a guarantee
concerning the properties of the material. No warranty or representation of any kind is
given with respect to the substantive or export laws of any other jurisdiction or country.
Please confirm that the information provided herein conforms to the substantive export or
other law of any other jurisdiction prior to export. Please contact Henkel Product Safety
and Regulatory Affairs for additional [Link] information is based on our current
level of knowledge and relates to the product in the state in which it is delivered. It is
intended to describe our products from the point of view of safety requirements and is not
intended to guarantee any particular [Link] data contained herein are furnished for
information only and are believed to be reliable. However, Henkel Corporation and its
affiliates (“Henkel”) does not assume responsibility for any results obtained by persons
over whose methods Henkel has no control. It is the user’s responsibility to determine the
suitability of Henkel’s products or any production methods mentioned herein for a
particular purpose, and to adopt such precautions as may be advisable for the protection of
property and persons against any hazards that may be involved in the handling and use of
any Henkel’s products. In light of the foregoing, Henkel specifically disclaims all
warranties, express or implied, including warranties of merchantability and fitness for a
particular purpose, arising from sale or use of Henkel’s products. Henkel further disclaims
any liability for consequential or incidental damages of any kind, including lost profits.
Others: The full text of all abbreviations indicated by codes in this safety data sheet section 3
are as follows:
H227 Combustible liquid.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
